Solabia acquires majority stake in BioActor

Solabia acquires majority stake in BioActor

Paris, France, January 12th, 2023

Press release
Solabia strengthens its position in the nutrition market with the acquisition of a majority stake in BioActor, a leader in the development and commercialisation of clinically proven natural active ingredients used by leading food supplement brands.

Founded in 2011 and located on the Maastricht Health Campus, BioActor is an innovation leader in the development and commercialisation of clinically evaluated polyphenols extracted from edible plants and fruits and used by leading food supplement brands worldwide.

Thanks to an in-house clinical research team with direct access to a state-of-the-art clinical research facility and a genuine passion for innovation, BioActor’s health ingredients are all first-in-class, offering supplement brands the opportunity to develop unique solutions to consumers worldwide. BioActor currently exports to more than 20 countries worldwide, serving leading brands across the nutrition and supplement industries.

Solabia is already present in the nutrition segment through original ingredients recognized for their health benefits, including Algatech’s microalgae-derived active ingredients. This strategic investment will allow Solabia to benefit from a wider range of ingredients and from BioActor’s expertise, strengthening its nutrition division positioning on this fast-growing market, as customers increasingly look for high quality active ingredients that combine naturality with proof of efficacy.

This new partnership will also support BioActor’s continued focus on R&D and product development, as well as the expansion of its production capabilities, enabling the company to serve the increasing global demand for its products. BioActor will become a centre of excellence for innovation and clinical research within Solabia’s nutrition division and the combination will allow both companies to benefit from the combined network and expertise, as well as to access new marketing channels and an expanded customer base.

Hans van der Saag, BioActor’s founder and CEO, retains a minority share and his role as CEO of BioActor.

Commenting on the acquisition, Jean-Baptiste Dellon, Chief Executive Officer of Solabia, said:
We are very impressed by BioActor’s dynamic team and innovation engine, and we are very pleased to welcome them to Solabia. BioActor’s pioneering R&D, impressive clinical research capabilities, market leading product portfolio and established customer base will allow us to further strengthen our position in the nutrition and food supplement markets. We are looking forward to working with BioActor to enhance growth for current product portfolio and accelerate the development of new ingredients.

Hans van der Saag, Founder & Chief Executive Officer of BioActor, commented:
We are excited to announce BioActor’s acquisition by Solabia. It marks a significant milestone for the company and the people behind its success, and it is an important step towards realising our mission to bring unique and clinically evaluated health ingredients to consumers worldwide. I am also thankful for the hard work and dedication of our employees. Together with Solabia, we are poised to extend the BioActor growth story as part of a larger organisation with an extensive global footprint, a shared commitment to innovation, research and development, and an unwavering focus on utilising the benefits of nutrition to elevate the health of all of us.

About Solabia
Solabia is a vertically integrated manufacturer of natural active ingredients for the cosmetics, nutraceutical, pharmaceutical, biotechnology and microbiology industries. With eight production facilities and multiple R&D centres, Solabia is a major player in the global cosmetics and nutraceutical ingredient markets with presence in North and South America, Europe, Asia, Middle East and Africa. Solabia also produces culture media, supplements, detection kits for the food testing and pharmaceutical industries and for microbiology laboratories.

More information about Solabia can be found at: https://www.solabia.com/en

About BioActor
BioActor is an innovation leader in the development, and commercialisation of clinically evaluated polyphenols extracted from edible plants and fruits. Based at the Maastricht Health Campus at walking distance from the largest nutrition & health faculty of The Netherlands and the Maastricht University Medical Center, the Company has an in-house clinical research team with direct access a state-of-the-art clinical research facility. Since its inception in 2011, BioActor has developed 8 branded health ingredients, supported by more than 20 clinical studies. The company currently exports its products to leading brands in more than 20 countries worldwide across the nutrition, food and beverages industries.

More information about BioActor can be found at: https://bioactor.com/

For more information, please contact:

Solabia
Françoise Pestretzoff
Email: francoise.pestretzoff@solabia.fr

BioActor
Hans van der Saag
Email: hans.vandersaag@bioactor.com


Aronia-Extract-Brainberry®-gains-US-patent-for-cognitive-performance-support

Aronia Extract Brainberry® gains US patent for cognitive performance support

Aronia Extract Brainberry® gains US patent for cognitive performance support

Maastricht, The Netherlands, November 16th, 2022

Press release
BioActor’s Aronia Extract, Brainberry®, has been granted a US patent for supporting cognitive function. The patent protects the composition and dosage of the ingredient and serves as official recognition of its ability to boost brain fitness and performance, which was demonstrated in two clinical trials.

Aronia-Extract-Brainberry®-gains-US-patent-for-cognitive-performance-support

US Patent for Aronia Extract Brainberry®

BioActor’s Aronia Extract, Brainberry®, has been granted a US patent for supporting cognitive function and, specifically, for improving reaction time and attention.

The patent protects the composition and dosage of the ingredient and serves as official recognition of its ability to boost brain fitness and performance.

Brainberry® is an all-natural ingredient derived from Aronia Melanocarpa berries from the Baltics and standardized for 15% Cyanidin-3-O-galactoside content: a powerful bioactive able to cross the blood-brain barrier and exerts multiple brain fitness benefits.

The supporting research

The ingredient is supported by two randomized, double-blind clinical trials carried out by BioActor, one in mid-age and one in younger subjects.

The two studies demonstrated Brainberry®’s beneficial effect on cognitive functioning after low-dose long-term (6 weeks and 12 weeks) and short-term acute (7 days) consumption.

Researchers found that Brainberry® increases attention/concentration, reaction time, psychomotor function, and visual-motor coordination.

Moreover, it was demonstrated that a beneficial effect in maintaining optimal levels of BDNF, an essential protein for brain health that is involved in neuronal plasticity and neuroprotection mechanisms.

The clinical research so far conducted, revealed that both middle-aged individuals, young students and professionals can benefit from the daily consumption of a low dose of Brainberry®.

Two additional studies to further investigate the benefits and elucidate the mode of action of Brainberry® are ongoing, thanks to the Public Private Partnership established between BioActor and Maastricht University.

About BioActor

BioActor is a life science company based on the Maastricht Health Campus and dedicated to researching, developing and commercialising health ingredients addressing healthy ageing and active living. BioActor has a targeted portfolio of patented and branded health ingredients that are all based on food crops, clinically researched and produced in Europe.

For more info: www.bioactor.com or www.brainberry.eu


three-laughing-women

New Open Label Study: Bonolive® shows increase in skin quality and menopause-related quality of life in postmenopausal women

New Open Label Study: Bonolive® shows increase in skin quality and menopause-related quality of life in postmenopausal women

Maastricht, The Netherlands, October 28th, 2022

Press release
BioActor recruited 23 Dutch and Italian postmenopausal women to assess their postmenopausal symptoms after 28 days of supplementation of Bonolive®. Self-assessed improvement of symptoms and skin quality were recorded after 14 days of supplementation. Symptoms such as feeling bloated, feeling anxious or nervous, mood swings and nail strength improved significantly, highlighting the effects of Bonolive® to benefit women’s health.

three-laughing-women

Postmenopausal symptoms and quality of life

During each woman’s life, many hormonal fluctuations occur, and they have an important impact on their quality of life. During and after menopause, these fluctuations can result in symptoms that can severely influence day-to-day tasks.

For many women, menopause-related symptoms include irregular periods, hot flashes, sweating, trouble sleeping, mood swings, irritability, skin dryness, and more. A lot of solutions are available, but an increasing number of women prefers a natural option to treat these postmenopausal symptoms.

Bonolive® is an olive leaf extract standardized for high oleuropein content, a powerful phytonutrient unique to the olive tree that offers a natural way in the management of menopause in its different phases.

The benefits of Bonolive® have been assessed in several clinical studies, which demonstrated its positive effect on bone, joint and cardiovascular health, as well as its strong antioxidant properties.

Open-label study in Post menopause women

Recently, BioActor has completed an open-label study on 23 postmenopausal women in the Netherlands and Italy, who consumed 250 mg of Bonolive® per day for 28 days.

In this open-label study, we aimed to investigate the short-term (28 days) effects of 250 mg/day Bonolive® supplementation on self-assessed postmenopausal symptoms in healthy post menopausal women (45 – 65 years). Participants were included in the study if they were healthy postmenopausal (i.e. no menstruation for at least 1 year) women with age between 45 and 65 years.

Study design open label study bonolive

The study results

Three times during the study (at baseline and at 14 and 28 days), participants had to complete an online questionnaire to self-assess their postmenopausal symptoms. After they filled in the questionnaire at baseline, they began their Bonolive® supplementation.

The results show that the participants experienced a significant improvement (P≤0.05) after 28 days of supplementation for specific postmenopausal symptoms: feeling bloated, feeling anxious or nervous, mood swings and night sweats. Furthermore, they indicated to notice and improvement in skin elasticity, skin hydration, nail strength and in energy and vitality.

* Sig (P≤0.05) compared to baseline.

 

Our consumer study demonstrates that short-term supplementation with 250 mg/day of Bonolive® results in significant beneficial effects on a wide range of post-menopausal symptoms. Therefore, we think that Bonolive® could be a meaningful addition to any nutritional supplement that aims to improve women’s quality of life during and after menopause.

After finishing her participation in the study one participant said:

“After Bonolive® supplementation, my skin is luminous and plumped too. My hair has fallen out less during this period. I would recommend Bonolive® to all my family and friends “

The participants reported that one of the advantages of Bonolive® is that it improved their skin quality and decreased their bloated feeling.

 

About BioActor

BioActor, based at the Maastricht Health Campus, Netherlands, is a life science company that has developed a range of proprietary bioactive ingredients for the nutrition & consumer health industries. The company focuses on the development of plant-based health ingredients for active living and healthy ageing. The goal is to provide the nutrition & consumer health industries with clinically tested innovations that confer a real health benefit to the consumer.

Feel free to contact BioActor via info@bioactor.com for more information on the possibilities Brainberry® has to offer.
Further information can be found on: www.bonolive.com and www.bioactor.com


MEET US - SupplySide West 2022

Visit us at SupplySide West 2022

October 25th, 2022

We are happy to announce that BioActor will participate in SupplySide West 2022, the premier gathering of health & nutrition professionals bringing together buyers and suppliers from throughout the industry. Visit us at Booth #2450!

Meet us at Booth #2450

Our team can’t wait to meet you in Las Vegas on November 2nd and 3rd.

You are welcome to come over for a coffee at our booth #2450 to discuss new business opportunities and get an idea of how our science-based ingredient can help you achieve your product development goals.

We are excited to discuss our nootropic ingredient for focus, Brainberry® or our recent studies on our innovative gut health ingredient MicrobiomeX®.

Don’t miss it, we are looking forward to seeing you there!

Book a meeting!



    Actiful-physical-and-mental-benefits

    Actiful® - New Publication Reveals Physical and Mental Health Benefits in Elderly

    Actiful® – New Publication Reveals Physical and Mental Health Benefits in Elderly

    Maastricht, The Netherlands, August 29th, 2022

    Press release
    A new randomized, double-blind, placebo-controlled clinical trial with Actiful® was recently published in the Journal of Nutrition, Health & Ageing. The study investigated whether Actiful® improves physical fitness and mental well-being in healthy elderly. Additionally, blood biomarkers for oxidative stress and endothelial function were measured. Key findings of the study were an improvement in handgrip strength, a measure of physical fitness, and psychological functioning facets, such as thinking, memory, learning, and concentration.

    Actiful-physical-and-mental-benefits

    The study

    The new research, published in the Journal of Nutrition Health & Ageing, was conducted by researchers at Maastricht University led by Dr Freddy Troost in collaboration with BioActor, the developer and manufacturer of the branded ingredient, Actiful®.

    Actiful® is a citrus flavonoid and pomegranate complex designed to boost vitality and support energy levels for an active lifestyle. The ingredient is standardised for its content in highly bioavailable 2S-hesperidin, an important citrus flavonoid which already showed in previous BioActor studies the efficacy in improving blood flow and sports performances in both highly trained and recreational athletes.

    The new study investigated whether daily supplementation with 700mg of Actiful® would affect physical fitness and psychological functioning in a healthy elderly population.

    As life expectancy increases rapidly, the elderly population is growing in numbers. Ageing is one of the main risk factors for a wide variety of diseases, such as cardiovascular disease, cognitive decline and reduced physical function. Therefore, strategies to support vitality in senior subjects are becoming increasingly relevant.

     

    The methods

    The study included 36 active seniors aged between 60-75 years old. The design of the clinical trial was a randomised, double-blind, placebo-controlled, crossover study. All participants received both treatments and placebo: four weeks of supplementation with Actiful® and four weeks of supplementation with the placebo, separated by a washout period of 4 to 8 weeks.

    During the intervention, participants completed the WHOQOL-100 questionnaire, a list of 100 questions created by the World Health Organisation and validated to assess the quality of life. In addition, a senior fitness test and handgrip measurements were performed, which are validated measures of physical performance.

    Furthermore, nitrate levels were measured as a marker of endothelial function. Nitrate is considered an important signalling molecule involved in endothelial function by inducing vasodilation, leading to improved blood flow.

    Oxidative stress was also evaluated by determining malondialdehyde (MDA) plasma levels. Oxidative stress is an imbalance between free radicals and antioxidants in your body and can damage cells, proteins and DNA, contributing to ageing.

     

    The results

    The study results indicate that four weeks of daily Actiful® supplementation significantly improved handgrip strength in healthy elderly. Handgrip strength is an important measure of physical fitness associated with reduced all-cause mortality, as well as increased cognitive function, mobility, and functional status.

    According to the researchers, a potential mechanism that might be associated with improving handgrip strength is improved mitochondrial function. In fact, the role of hesperetin – the main metabolite of Actiful®, in mitochondrial functioning, increased intracellular ATP production, and mitochondrial spare capacity was already observed in vitro.

    “With age, the number and functionality of mitochondria decreases. Dysfunctional mitochondria have reduced the capacity for producing ATP – our muscles’ principal energy source. Therefore, the next step is to confirm the effect of Actiful® on mitochondrial biogenesis and functionality in humans in vivo”, the researchers commented.

    In addition to the handgrip strength, also psychological function improved after the 4 weeks of supplementation with Actiful®.

    Specifically, the researchers found a significantly higher score for the treatment group than the placebo in the thinking, memory, learning, and concentration facet. As the quality of life is an important factor in successful ageing, improved psychological functioning is deemed increasingly relevant.

    MDA and NO3 were also analysed as a measure of oxidative stress and endothelial functions. After supplementation, plasma MDA decreased compared to the placebo, a sign of improved oxidative stress status.

    Finally, higher production of NO3 was observed. NO3 is an important signalling molecule involved in endothelial function by causing vasodilation in smooth muscle cells and can contribute to improving blood flow and exercise capacity, as demonstrated in previous studies.

    Overall, the study results suggest that Actiful® consumption results in improved physical performance and better quality of life, which are two crucial factors in successful ageing.

    We are pleased with the results of this clinical trial, which includes improvements both in physical fitness and mental well-being, as well as improved oxidative stress markers. These results have piqued our interest regarding potential underlying mechanisms of action, which are currently being investigated in our new clinical trial.” Commented Sanne Ahles – clinical researcher at BioActor.

     

    Opportunity for innovation

    Actiful® has been developed to support vitality and energy levels contributing to healthy ageing. The active ingredient can already be found in various products on the market worldwide. Actiful® is easy to formulate, and it can be added to a wide variety of dietary supplements in several convenient formats, including gummies, effervescent tablets, capsules, ready-to-use sachets and drinks.

     

    About BioActor

    BioActor, based at the Maastricht Health Campus, Netherlands, is a life science company that has developed a range of proprietary bioactive ingredients for the nutrition & consumer health industries. The company focuses on the development of plant-based health ingredients for active living and healthy ageing. The goal is to provide the nutrition & consumer health industries with clinically tested innovations that confer a real health benefit to the consumer.

    Feel free to contact BioActor via info@bioactor.com for more information on the possibilities that Actiful® has to offer.
    Further information can be found on: www.actiful.eu and www.bioactor.com


    man-training

    The effects of Hesperidin on exercise performance - New publication from BioActor in collaboration with Maastricht University

    The effects of Hesperidin on exercise performance – New publication from BioActor in collaboration with Maastricht University

    Maastricht, The Netherlands, July 22nd, 2022

    Press release
    The review recently published in Nutrients was conducted by BioActor in collaboration with Maastricht University and examined the potential mechanisms through which hesperidin can improve exercise performance.

    man-training

    A review on hesperidin and exercise performance

    Nutrients, a leading peer-reviewed scientific journal of human nutrition, has recently published a review about hesperidin’s effect on exercise performance. The research was conducted by M. Imperatrice, a clinical researcher at BioActor, in collaboration with the Maastricht University’s Department of Human Biology.

     

    This review collects the results of randomized controlled trials (RTCs), animal studies, and in vitro studies providing more evidence on how hesperidin, a flavanone abundantly present in citrus fruits, could lead to enhancement in exercise performance.

     

    According to the review’s results, hesperidin is able to improve endothelial function (via increased NO availability), inhibit ROS production, decrease production and plasma levels of pro-inflammatory markers, and improve anaerobic exercise outcomes (e.g. power, speed, energy).

     

    We are really proud to share the results collected in our review about the potential mechanisms linking hesperidin to enhanced anaerobic performance, namely improved endothelial function, reduced exercise-induced oxidative stress, and inflammation. For elite and recreational athletes, hesperidin could be a promising food supplement to optimize the oxygen and nutrient supplies of the muscles, stimulate muscle contraction, and enhance muscle recovery between training sessions. The ergogenic effects that hesperidin can bring to the spectrum of improved exercise performance are promising and should be investigated further. With our “Actiful 2” ongoing Clinical Study, we are going to deepen this knowledge by investigating both the effects of hesperidin supplementation on endurance exercise and on changes in intramuscular markers via skeletal muscle biopsies.” said M. Imperatrice.

     

    BioActor’s interest in hesperidin has resulted in the development of two active ingredients. The first ingredient branded under the name WATTS’UP® and targeting sports performance has already been tested in two randomized placebo-controlled clinical trials, one with highly trained athletes and one with moderately trained subjects. The second ingredient goes under the name Actiful® and targets energy and vitality. This ingredient has already been tested in randomized placebo-controlled clinical trials, in elderly subjects, showing physical and mental benefits.

     

    About BioActor

    BioActor, based at the Maastricht Health Campus, Netherlands, is a life science company that has developed a range of proprietary bioactive ingredients for the nutrition & consumer health industries. The company focuses on the development of plant-based health ingredients for active living and healthy ageing. The goal is to provide the nutrition & consumer health industries with clinically tested innovations that confer a real health benefit to the consumer.

    Feel free to contact BioActor via info@bioactor.com for more information on the possibilities WATTS’UP® and Actiful® have to offer.
    Further information can be found on: www.wattsup.eu, www.actiful.eu and www.bioactor.com


    Basketball player

    New Open Label Study: Brainberry® shows cognitive and performance benefits in professional basketball players.

    New open-label study: Brainberry® shows cognitive and performance benefits in professional basketball players.

    Maastricht, The Netherlands, July 1st, 2022

    Press release
    BioActor recruited 35 professional Greek male and female basketball players to assess their cognitive and basketball-specific skills after an acute and one-week intake of Brainberry®. Notably, cognitive performance linked to focus, reaction time and hand-eye coordination improved acutely and following a one-week intake. Also, basketball-specific skills like shooting, rebounding and dribbling improved significantly, underlining the ability of Brainberry® to benefit sports performance.

    Basketball player

    Open-label study in professional basketball players

    According to the F.I.B.A. (Fédération Internationale de Basketball), more than 450 million people play basketball worldwide, and about 70.000 of them are professionals. In the US, basketball is one of the most followed sports, and according to Statista, the National Basketball Association (NBA) generates about $6 to $8 billion in revenue per season.

    Especially at the top level, nutritional strategies to improve cognition are key to succeeding in this sport. A professional basketball player needs to combine cognitive and physical skills and react to different situations during the game. Moreover, since players need to communicate with each other and their coach while performing, the cognitive load involved in this sport is massive.

    Brainberry® is a nootropic ingredient developed by BioActor to help consumers improve their brain fitness in a natural and safe way. More specifically, Brainberry® is an Aronia berry extract from the Baltics, standardized for high levels of cyanidin-3-O-galactoside.

    BioActor already conducted 2 double-blind placebo-controlled clinical studies which demonstrated cognitive benefits in middle-aged healthy individuals and in young healthy individuals.

    Moreover, in a previous open-label study, Brainberry® improved cognitive performance of amateur gamers. The study revealed that gamers can benefit from the consumption of Brainberry® and improve their gaming skills such as eye-hand coordination and focus.

    In follow up to these studies, BioActor now completed another open-label study on 35 professional basketball players in Greece, who consumed 65 mg of Brainberry® for seven days. Basketball is characterized by highly intermittent actions with changes in movement type every 1-2 seconds. Particularly at the highest level, the combination of gross and fine motor skills along with cognitive functions and psychomotor control is key to success. Female and male professional basketball players were selected from teams that participate in the first Greek basketball league.

    The objective of the study was to investigate the effect of a daily intake of a capsule containing 65mg of Brainberry® on overall cognitive and basketball-specific skills.

    The study results

    During the three time points, Baseline (Time 0), Acute (Time 1) and 7 days (Time 2), the participants had to fill out a questionnaire with specific questions aiming at assessing cognitive skills, basketball-specific skills, mood, and sleep quality. At Time 0, the participants did not consume Brainberry®, in order to generate a baseline measurement for their self-reported skills during a basketball session.

    The results show that the basketball players who participated in the study experienced a significant improvement (P < 0.05) from day one, in terms of cognitive: focus, reaction time and eye-hand coordination; and basketball-specific skills: shooting, rebounding, and dribbling. At the same time, no significant differences were found in their speed and quality of sleep was not affected.

    Results-of-Brainberry-in-basketball-players

    *Sig (P < 0.05) baseline vs acute; **Sig (P < 0.05) baseline vs after 7 days and ***Sig (P < 0.05) acute vs 7 days

     

    With this additional study, which highlights the ability to enhance cognitive and basketball-specific skills, Brainberry® taps into the sports nutrition segment, where already some sports nutrition brands have adopted the ingredient and formulated products targeting brain fitness for athletes.

    Vasiliki Louka, a professional basketball player that belongs to the women’s national Greek team stated:

    “Brainberry® surprised me in a good way. This month was really tiring and stressful, especially for the athletes competing for the national team. I felt more focused during my training and considering that Brainberry® contains only natural ingredients, it makes it an interesting choice.”

    Furthermore, the participants reported that one of the advantages of Brainberry®, compared to the most common caffeine-based supplements that they have been using, is that Brainberry® did not affect their quality of sleep and, at the same time, helped them decrease their stress level.

     

    About BioActor

    BioActor, based at the Maastricht Health Campus, Netherlands, is a life science company that has developed a range of proprietary bioactive ingredients for the nutrition & consumer health industries. The company focuses on the development of plant-based health ingredients for active living and healthy ageing. The goal is to provide the nutrition & consumer health industries with clinically tested innovations that confer a real health benefit to the consumer.

    Feel free to contact BioActor via info@bioactor.com for more information on the possibilities Brainberry® has to offer.
    Further information can be found on: www.brainberry.eu and www.bioactor.com


    prebiotics-and-probiotics

    MEET US - BioActor Presenting MicrobiomeX® and Naxus® at the 15th Annual IPC conference

    MEET US – BioActor Presenting MicrobiomeX® and Naxus® at the 15th Annual IPC conference

    Maastricht, The Netherlands, June 16th, 2022

    Press release
    The 15th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health – IPC2022 will be held during 27 – 30 June 2022 in Bratislava. BioActor is an active contributor and confirmed partner of this conference. Hans van der Saag (CEO) will present on our ingredient Naxus®, a prebiotic with metabolic and immune effects, and Yala Stevens (CSO) presents the clinical and mechanistic research on MicrobiomeX® in irritable bowel syndrome (IBS) patients and elderly subjects.

    prebiotics-and-probiotics

    BioActor Presenting MicrobiomeX® and Naxus® at the 15th Annual IPC conference

    The 15th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health – IPC2022 will be held during 27 – 30 June 2022 in Bratislava.

    The IPC conference is the world’s biggest scientific conference that focuses solely on basic and applied research of probiotics, prebiotics, gut microbiota and health. More than 400 scientists from over more than 80 countries have attended the conference last season.

    The scientific program will focus on current advances in the research, production and use of probiotics and prebiotics with particular focus on their role in maintaining health and preventing diseases. At IPC, leading scientists from industry and academia present current advances in understanding and influencing the interaction between gut microbiota and human health.

    The conference enables the interactive exchange of state-of-the-art knowledge. It is focused on evidence-based benefits, health claims proven in scientific experiments and clinical trials.

    BioActor is an active contributor and confirmed partner of this conference. Hans van der Saag (CEO) will present on our ingredient Naxus®, a prebiotic with metabolic and immune effects, and Yala Stevens (CSO) presents the clinical and mechanistic research on MicrobiomeX® in irritable bowel syndrome (IBS) patients and elderly subjects.

    Naxus® presentation by Hans van der Saag (CEO)

    Naxus® is a native arabinoxylan extract from the wheat endosperm. It is a powerful and well-tolerated prebiotic with metabolic and immune effects. Due to its complex branched structure, Naxus® is slowly and selectively fermented by multiple species of the microbiota, inducing a remarkable bifidogenic effect without causing gas formation and intestinal discomfort. It induces a remarkable microbiota shift and increased short-chain fatty acids production, with proven effects on immune health and glycemic control.

    MicrobiomeX® presentation by Yala Stevens (CSO)

    MicrobiomeX® is a natural extract from citrus fruit designed to beneficially modulate the microbiome composition in the gut. It’s a first-in-class Flavobiotic® that protects the gut barrier and directly leverages the gut microbiome’s potential. This results in enhanced immune health, as well as anti-inflammatory effects.

    IBS is a functional gastrointestinal disorder with various symptoms including pain and discomfort in the abdomen. Also, elderly often develop imbalances in their gut microbiota and often experience discomfort.

    Patients with IBS and elderly would benefit substantially from treatments that could relieve their symptoms and improve their gut health. The flavonoids in MicrobiomeX® have the potential to benefit individuals with gastrointestinal conditions because of its antioxidant and anti-inflammatory properties.

    Business opportunities

    The IPC conference is a great opportunity to reconnect with colleagues from all over the world and make new contacts. Hans van der Saag (CEO) and Yala Stevens (CSO) will be there to represent BioActor’s portfolio, with a focus on our gut health ingredients. Feel free to pass by at any time to chat about our innovative ingredients for gut health support!

    We look forward to meeting you in Bratislava!

    The IPC 2022 conference will take place from 27 to 30 June 2022.

    Where: Hviezdoslavovo námestie 3, 811 02 Bratislava, Slovakia

    About BioActor

    BioActor, based in Maastricht, Netherlands, is a product development company that supplies proprietary bioactive formulations to the nutrition & healthcare industry. The company focuses on the development of innovative bioactives that address active living and healthy ageing. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

    For further information, see www.bioactor.com or visit https://microbiomex.com/ or https://naxus.nl/


    BioActor-showcasing-WATTS’UP-at-the-19th-Annual-ISSN-Conference

    MEET US - BioActor showcasing WATTS’UP® at the 19th Annual ISSN Conference

    MEET US – BioActor showcasing WATTS’UP® at the 19th Annual ISSN Conference

    Maastricht, The Netherlands, June 3rd, 2022

    Press release
    The International Society of Sports Nutrition (ISSN) is organizing their 19th Annual Conference and Expo. BioActor is an active contributor to this conference and Yala Stevens, our chief scientific officer will present the clinical results on our ingredient WATTS’UP®.

    BioActor-showcasing-WATTS’UP-at-the-19th-Annual-ISSN-Conference

    BioActor showcasing WATTS’UP® at the 19th Annual ISSN Conference

    The International Society of Sports Nutrition (ISSN) is the world’s leader in providing science-based sports nutrition and supplement information. This year they are organizing their 19th Annual Conference and Expo. Anyone interested in sports science/nutrition can attend!

    The conference addresses a diverse audience such as researchers, students, dieticians, sports nutritionists, but also the athletes themselves. Therefore, the conference offers a platform to discuss various hot topics related to sports nutrition, such as sports supplements, elucidation of the physiological mechanisms behind nutraceutical interventions, as well as nutritional effects on performance.

    The strength of the annual ISSN conference is that top researchers present on novel paradigms in sports nutrition. Besides, it is also an excellent opportunity to make new contacts and reconnect with colleagues from all over the world.

    BioActor is an active contributor to this conference, since Yala Stevens, our chief scientific officer will present the clinical results on our ingredient WATTS’UP®. Title of the study: The effect of citrus flavonoid extract supplementation on anaerobic capacity in moderately trained athletes: a randomized controlled trial.

    Original research paper presentation by Yala Stevens (CSO)

    Previous studies have demonstrated that supplementation with flavonoids from citrus fruits may be an effective strategy to improve exercise performance in male athletes. Repeated intake of 500 mg of a specific citrus fruit extract improved aerobic exercise performance. Also, an increased absolute power output and a decreased oxygen consumption/power ratio were observed.

    Yala will be presenting new insights on the beneficial effects of 400 mg and 500 mg citrus fruit extract (WATTS’UP®) supplementation on short-term high-intensity exercise performance. In this study, we used a WinGate protocol, the gold standard for testing high-intensity performance for 92 male and female participants.

    Join us on Friday 17th of June at 10:10am for Yala’s presentation in the Westin Fort Lauderdale Beach Resort (Florida).

    Business opportunities

    BioActor will also be present with a small table top, together with the exclusive distributor for the US market, SEPPIC Inc. Jeremie Feuer (SEPPIC) and Joris Kretzers (BioActor) will be there to represent BioActor’s portfolio, with a specific focus on our sports nutrition ingredients. If you are looking for natural ingredients that benefit athlete’s performance, feel free to pass by at any time on Thursday or Friday for a chat!

    We look forward to meeting you in Fort Lauderdale!

    The ISSN conference and expo will take place from June, 16-18 2022.
    Westin Fort Lauderdale Beach Resort, 321 North Fort Lauderdale Beach Blvd., Fort Lauderdale Florida USA 33304

    About BioActor

    BioActor, based in Maastricht, Netherlands, is a product development company that supplies proprietary bioactive formulations to the nutrition & healthcare industry. The company focuses on the development of innovative bioactives that address active living and healthy ageing. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

    For further information, see www.bioactor.com or visit www.wattsup.eu


    MicrobiomeX® nominated as finalist for 2022 NutraIngredients-USA ‘Ingredient of the Year’

    MicrobiomeX® nominated as finalist for 2022 NutraIngredients-USA ‘Ingredient of the Year’

    Maastricht, Netherlands, June 2nd, 2022

    Press release
    BioActor is delighted to share that MicrobiomeX® was nominated as a finalist for the 2022 NutraIngredients-USA ‘Ingredient of the Year’ in the category Prebiotic. NutraIngredients-USA Awards honour the best and brightest in ingredients, finished products, companies, people and initiatives in the nutrition and dietary supplements industry.

    MicrobiomeX-is-a-finalist-for-the-NutraIngredients-Awards

    Finalist for 2022 NutraIngredients-USA ‘Ingredient of the Year’

    We are excited to announce that MicrobiomeX® was nominated as a finalist for the 2022 NutraIngredients-USA ‘Ingredient of the Year’ in the category Prebiotic.

    The NutraIngredients brand has led the online news source in the nutrition industry for over 19 years, providing insights into the functional food and supplement market in North America, ranging from investments and innovation to ingredients, product formulation, regulation, consumer trends and more!

    Specifically, NutraIngredients-USA Awards honour the best and brightest in ingredients, finished products, companies, people and initiatives in the nutrition and dietary supplements industry. With a focus on innovation, long-term market success and state-of-the-art research, it is an honour that MicrobiomeX® was nominated a finalist!

    MicrobiomeX® is a first-in-class Flavobiotic® that has been clinically proven to improve the SCFA profile, lower gut inflammation and enhance immunity through its precision prebiotic effect. Beneficial changes in the microbiota are induced at a low dose of 250-500 mg, and MicrobiomeX® is stable with probiotics.

    “Special thanks goes out to our US distributor SEPPIC with whom we collaborated to get there”, says Joris Kretzers, Sales Manager Western Europe & North America of BioActor. “We are very proud of this achievement and are looking forward to the winner announcement in July!”

    About BioActor

    BioActor, based at the Maastricht Health Campus, Netherlands, is a life science company that has developed a range of proprietary bioactive ingredients for the nutrition & consumer health industries. The company focuses on the development of plant-based health ingredients for active living and healthy ageing. The goal is to provide the nutrition & consumer health industries with clinically tested innovations that confer a real health benefit to the consumer.

    Feel free to contact BioActor via info@bioactor.com for more information on the possibilities MicrobiomeX® has to offer.

    Further information can be found on:  www.microbiomex.com and www.bioactor.com